Developmental origin and subtype function of cardiac macrophages. Embryonic development (E7.5-E12.5) revolves around the hematopoietic endothelium (HE) of the yolk sac (YS), which undergoes three ...

Heart failure, a leading cause of death in industrialized nations, is caused by damage to or loss of contracting cardiac muscle cells known as cardiomyocytes. Wei and colleagues 1 recently described a ...

Heartseed dosed the 1st patient in its trial of HS-005, the world's 1st catheter delivery of iPSC-derived cardiomyocyte ...

The heart is like a high-octane engine. Fueled by fatty acids, cardiomyocytes have abundant mitochondria to rev up ATP production through oxidative phosphorylation and keep the engine humming. However ...

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair. The findings underscore the critical role of ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, a ...